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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
12.42
Human Site:
S1508
Identified Species:
22.78
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
S1508
S
E
K
E
T
E
I
S
T
I
Q
K
Q
L
E
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
S1508
S
E
K
E
T
E
I
S
T
I
Q
K
Q
L
E
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
S1508
S
E
K
E
T
E
I
S
T
I
Q
K
E
L
E
Dog
Lupus familis
XP_852631
1216
141588
W181
T
S
D
M
A
L
K
W
I
T
K
G
E
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
L1436
L
C
E
K
Q
E
E
L
T
R
K
E
T
S
E
Rat
Rattus norvegicus
Q7TSP2
1385
159522
T350
G
S
R
C
F
G
E
T
L
S
T
L
N
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
E1115
E
L
L
H
L
R
E
E
L
S
Q
A
K
K
K
Frog
Xenopus laevis
NP_001080954
2954
339950
Q1697
T
Q
E
K
K
E
L
Q
Q
T
H
E
H
L
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
S978
I
E
E
D
N
R
Q
S
D
A
T
E
P
I
C
Honey Bee
Apis mellifera
XP_001121311
1418
164919
V383
E
L
L
K
T
R
I
V
S
G
D
N
T
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
E1440
N
D
K
E
S
G
A
E
D
K
A
T
E
L
E
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
S212
D
R
T
G
D
E
D
S
S
N
S
C
D
A
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
E313
L
A
P
I
H
A
D
E
T
K
S
S
L
Q
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
93.3
0
N.A.
20
0
N.A.
N.A.
6.6
13.3
N.A.
N.A.
13.3
13.3
N.A.
26.6
P-Site Similarity:
100
100
100
20
N.A.
46.6
13.3
N.A.
N.A.
20
53.3
N.A.
N.A.
40
33.3
N.A.
53.3
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
0
0
8
8
8
0
8
8
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
8
8
8
8
8
0
16
0
16
0
8
0
8
0
0
% D
% Glu:
16
31
24
31
0
47
24
24
0
0
0
24
24
0
39
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
8
0
0
8
0
16
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
8
0
0
8
0
0
31
0
8
24
0
0
0
8
0
% I
% Lys:
0
0
31
24
8
0
8
0
0
16
16
24
8
16
8
% K
% Leu:
16
16
16
0
8
8
8
8
16
0
0
8
8
39
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
0
0
8
0
8
8
8
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
0
8
0
8
8
8
0
31
0
16
8
8
% Q
% Arg:
0
8
8
0
0
24
0
0
0
8
0
0
0
0
0
% R
% Ser:
24
16
0
0
8
0
0
39
16
16
16
8
0
8
0
% S
% Thr:
16
0
8
0
31
0
0
8
39
16
16
8
16
0
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _